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Post-Doctoral Scientist, Biologics Analytical Operations

Company: Gilead Sciences, Inc.
Location: Oceanside
Posted on: November 25, 2022

Job Description:

Post-Doctoral Scientist, Biologics Analytical OperationsUnited States - California - OceansideGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.Making an impact on a global scaleInclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly For Current Gilead Employees and Contractors:Please log onto your Internal Career Site to apply for this job.Job DescriptionSummary:The Oceanside Potency and Function Characterization group is looking for a highly motivated Post-Doctoral Scientist to pursue cutting-edge drug development work on therapeutic biologics.Responsibilities:The successful candidate will initiate an independent research project to develop in vitro and cell-based assays to determine binding constants and rates of internalization of recombinant mAbs or Fc-fusion model molecules containing different glycosylation patterns and in collaboration with the DMPK group, develop models explaining PK trends observed for these model molecules and monitor in vivo selective clearance of glycoforms in murine studies. The expectation is that this work will result in novel contributions to our understanding of impact of glycosylation on pharmacokinetics of the molecule of interest. The selected candidate will work in a highly collaborative environment at Gilead through a 2-year term, with an option to extend an additional third year. It also provides access to world class research facilities and the opportunity to leverage expertise and resources across multiple functional areas at Gilead.Minimum Qualifications:

  • Candidate should possess a Doctoral degree and have a strong background in either biochemistry, immunology, pharmacology, or a related area.
  • Qualified candidates must have at least one first author paper published or accepted in a peer-reviewed journal.
  • Candidates with strong skill set in mammalian cell culture, cell-based assays and ELISA.
  • Good organizational skills, attention to detail, and collaborative communication skills are essential.Preferred Qualifications:
    • Previous research experience in cellular and molecular immunology would be preferred.
    • Understanding of protein chemistry and glycosylation is a plus.
    • Previous research experience in glycosylation characterization by LC-MS or other glycan characterization methods.
    • Understanding of basic pharmacokinetics of protein therapeutics.For jobs in the United States:As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. "Full vaccination" is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation. For more information about equal employment opportunity protections, please view the 'EEO is the Law' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.For Current Gilead Employees and Contractors:Please log onto your Internal Career Site to apply for this job.

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Keywords: Gilead Sciences, Inc., Oceanside , Post-Doctoral Scientist, Biologics Analytical Operations, Other , Oceanside, California

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