Bioprocess Manufacturing Technician
Company: Hoffmann-La Roche Ltd
Location: Oceanside
Posted on: August 3, 2022
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Job Description:
The Position
At Genentech, we are dedicated to pursuing groundbreaking science
to discover and develop medicines for people with serious and
life-threatening diseases.
As a Bioprocess Manufacturing Technician, you will be responsible
for producing medicine in a highly automated and controlled
environment. Each product has a specific recipe; you will follow
this recipe, along with the standard operating procedures, to
operate the production equipment across various areas, including
raw material dispensing/aliquoting, cell culture and purification.
You will maintain records and follow all the steps necessary to
comply with regulatory requirements within a current Good
Manufacturing Practices (cGMP) environment.
This is a contract role with the possibility of conversion to a
permanent employee position.
There are 3 main production areas within manufacturing:
* Production Services - responsible for weighing and aliquoting of
raw materials and small scale solution prep. Also responsible for
washing, autoclaving, and preparation of small equipment parts and
assemblies.
* Upstream Manufacturing - responsible for cell growth, from
inoculation in spinner flasks, managing growth all the way through
large scale bioreactors.
* Downstream Manufacturing - responsible for the purification of
cellular harvest utilizing chromatography and reformulation
techniques, as well as preparation of product for shipping to final
fill/finish sites.
As a new member of the team, you'll typically be assigned to one of
the three production areas. This will allow you to build
capabilities and work on increasingly complex technical
assignments, with the potential to rotate into future production
areas as you gain experience.
Job Responsibilities
Safety is paramount to both our employees and our patients, and is
therefore at the core of all job responsibilities. This includes
complying with all safety requirements, cGMP, Standard Operating
Procedures (SOP) and manufacturing documentation. You must
immediately report any and all safety and environmental incidents,
including injuries, illness, near miss & safety suggestions.
Additional responsibilities may include:
* Utilizing automated systems to operate, clean and sterilize
production equipment
* Operating small-scale cell culture areas and systems by using
aseptic techniques, maintaining cell banks; and performing general
seed lab operations
* Operating fermenters, centrifuges, other harvest systems and
protein purification units
* Operating and cleaning fixed tank and filtration systems
* Operating large scale column chromatography systems
* Preparing solutions required for the production process (media
and buffer make-up)
* Cleaning, assembling, and sterilizing equipment for production by
operating glass washers and autoclaves
* Executing environmental monitoring throughout the facility
Ideal Candidate Attributes
* You're a quick learner and can receive, digest and interpret
instructions with ease
* You're technically and mechanically inclined and can learn new
systems and technology quickly
* You find joy in the details and pride yourself in accuracy
* You can work independently but as part of a larger team
* You can demonstrate the ability to independently document and
record information
* You showcase good judgement and ability to recognize non-routine
problems/deviations and escalate to partner on potential
solutions
* You demonstrate increasing technical competency through training
and operational procedures of at least one manufacturing
department
Shift Details
We have a variety of 12-hour shifts to support our 24x7 facility
operations. Staff working over 8 hours in a day will be paid
overtime in accordance with local and state laws. In addition,
staff working night shifts will be paid a shift differential. While
we are occasionally able to accommodate shift requests, candidates
with open availability will be given priority consideration as we
are not able to guarantee shift placement.
* Frontside Days: Sunday thru Tuesday and alternating Wednesdays
6:00am-7:00pm
* Backside Days: Thursday thru Saturday and alternating Wednesdays
6:00am-7:00pm
* Frontside Nights: Sunday thru Tuesday and alternating Saturdays:
6:00pm-7:00am
* Backside Nights: Wednesday thru Friday and alternating Saturdays:
6:00pm-7:00am
* Frontside Swings: Sunday thru Tuesday and alternating Wednesdays
1:00pm-2:00am
* Backside Swings: Thursday thru Saturday and alternating
Wednesdays 1:00pm-2:00am
Additionally, Production Services has a four-day 10-hour shift.
* Frontside Days: Sunday thru Wednesday 8:00am-6:30pm
* Backside Days: Wednesday thru Saturday 8:00am-6:30pm
Physical Requirements
* You'll be on your feet for 8 to 11 hours of the day and will be
required to wear Genentech-provided, lab approved steel toe
shoes
* Our facility is expansive - you may climb multiple flights of
stairs daily
* You should be able to lift up to 25lbs on the rare occasion
* You will work in a clean room environment; you will be required
to gown up in the form of hospital scrubs, bunny suits, gloves,
hair net, mask, safety glasses, hearing protection
* No makeup or jewelry can be worn when working in the clean room
environment
* You may work with hazardous materials and chemicals
Educational Requirements
* High school diploma or equivalent
* Preferred - Degree in Life Sciences/Engineering, Associate's or
Biotech certificate from approved program
To complete the initial video interview, please visit:
https://www.sparkhire.com/job/a19599c0-c5fa-4d2a-aa29-039ac147a81f
To learn more about the manufacturing process, please watch this
video: https://www.youtube.com/watch?v=sxvJatvqBVE
Please note: We currently do not sponsor work visas for this
position or offer relocation assistance.
#LI-AI1, #ptcareers
Who we are
A member of the Roche Group, Genentech has been at the forefront of
the biotechnology industry for more than 40 years, using human
genetic information to develop novel medicines for serious and
life-threatening diseases. Genentech has multiple therapies on the
market for cancer & other serious illnesses. Please take this
opportunity to learn about Genentech where we believe that our
employees are our most important asset & are dedicated to remaining
a great place to work.
Unless entitled to a reasonable accommodation under applicable law,
employees are required to be fully vaccinated against COVID-19 in
accordance with customer requirements, the company's health and
safety obligations and/or applicable law or guidelines.
Diversity and Inclusion (D&I) are critical to the success of
our company and our impact on society. We believe that by
championing diversity of background, thought and experience, we can
foster a sense of belonging and provide an environment where every
employee feels valued, included, and able to contribute their best
for the patients we serve. We're focused on attracting, retaining,
developing and advancing our people to their full potential by
rewarding bold ways of thinking and integrating inclusive behaviors
into every aspect of our work.
Genentech is an equal opportunity employer, and we embrace the
increasingly diverse world around us. Genentech prohibits unlawful
discrimination based on race, color, religion, gender, sexual
orientation, gender identity or expression, national origin or
ancestry, age, disability, marital status and veteran status. For
more information about equal employment opportunity, visit our
Genentech Careers Homepage.
Keywords: Hoffmann-La Roche Ltd, Oceanside , Bioprocess Manufacturing Technician, Professions , Oceanside, California
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